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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0331f6b18a5656714828acb5d36e56b0c7aacd8218eee22d66b39b103fd831de' 
  AND token = '94YLTRSTHVtMCS5VkcsiOSKxU5UrnylEO0OAoyvTc8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}