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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35d5e0c6b4979e20dc237a12562c76483d4fd56c5698e1170dce9814749b6d48' 
  AND token = 'ZzADX+e+st4AvVXXqDdO9IESlCVAKbruSQnXS8IZ67w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}