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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4181bc9d52046468949f68175fee6cb2f6c9364a39c9ea04f255aac05862cfee' 
  AND token = '1I0d/dgPwARlkBBlbbmrKJuBg3A8jNnwdkAR/iTZZA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}