SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c399226c56efbb968abfab282180a57aa4e6cf6de50abf808ebe0eb33f12f10b' 
  AND token = 'QD8PLWHbMPEey0jGIOhKdHSleJmJ83HZDruGkF5keHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}