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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b2eb99733e5d6e390dcde2295453c85f69308239d7f4e006ac644859973aeb1' 
  AND token = 'FLys+08jOSP446H0SquqZCmYSifiL5t37lhWoS00fyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}