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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ab14140c73524cab3e74f9ad7e21748be88b5b56d0a4e5addc5fd8faf7aeb3' 
  AND token = 'TjwhyEwq2/+0y+oMUHegpzRToM/zvSnWTkqlwCqQ2kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}