SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5325425bf72b0643550b53a73f3f527c4b90d0373fb2b4311e64c6dc609161' 
  AND token = 'joSZahr0lYrO4/zaJqs5OQwFLZCrjaqarMjYgn1h9vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}