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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73506446f53a05ace37eb49dc6513448a2e4e5c4f4e066fa3973587db7199a6' 
  AND token = 'hgsON9lkwIQzdGI02OsQc9GXHbfNT0Ti1Ydq+s0cYwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}