SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4242fc9781368b3f2df286bae470d4de10e1ad1e30d8b98a5c247e7ca344a553' 
  AND token = 'lxyqABTJHt3weCGrFLQRKskUfOxKsDgEQZgE4bRPSTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}