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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff2248b85de67986f5a8658dafd1d62e5aea05e667f64d5aad4ba064efed4de0' 
  AND token = 'JZzKITOTRBRquQxvI+XJEgwGZasEEaWlbw5FlrYX3bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}