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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be8cb3b3a66f7aa429ce49e397d4025a55298b51aa4140ad5b903a795c73dfe' 
  AND token = 'a47Mn17SxE1BOSvUY27BZMMO2ICOiuoeCOaJdJAp7Vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}