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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eefbe0a7f8672315770e4e2f12bd98e7ff2ffab096bf95b56d5081a8e772c1d' 
  AND token = '1MBqFR6TnvPxMA5IuQLvN75A9FY9eg3AfGMCfHnzSRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}