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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389b93e85b1fde8024ce0d1cf015d4b3f913f2b8a6ad912387b14faf0509d3f7' 
  AND token = 'vWF6o8uRDT9C4+lrXuT5m+E24DSHmDblTubEysyVrbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}