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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa8332f09a7824cc1eeae7efd2a0a04fc1932bc11ec018238d24f5b5534a9380' 
  AND token = '5iGixz19LZv3PgqF0LLHNBGK3knH0qhhuL424aXkDx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}