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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b0cf0845faed6e78bbe266c243da33cbec104d4c63d5f16eefd1f14446e0c2b' 
  AND token = '3gOVi6akLLLKphK/q5zI1/iMfjq3aBy9emhVEvfsR/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}