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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d228d914eedc93ce82399713927926f0bf14e6952004e780f28fbbb82ac5733' 
  AND token = 'ReN9KsuqDD+ajkpDFzoeC55g6Bonr7FhA/IeZumYeeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}