SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489e3b77f9f7109b809dabbe7e43338ff93063d317e4e551363a91b706e3c325' 
  AND token = 'LFH4g4zOe+OBljAMHrvOT5/iC3Rg7put8dxpnOXMwyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}