SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad01b7bff06551f584b8a8df1ac41c0343665d2bd87063cab0a3504824f3bf0a' 
  AND token = 'JIL0OewN6lB93jDGnXLEXWGhBDtZd6DLsUIYdpgDi3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}