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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d1170bc90bf1ff6e7244b6eff67c045be74e720a0eb2a15d9988d4e75ebb66' 
  AND token = 'CVXSdSW9TZRichdT6zYM8O+FIVjIVApRFPioGGq1GkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}