SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5cb90f96189abe46ad03e4505d5113296368f77bb6d67f2fd71090b08ef4d7' 
  AND token = 'xC27O3Sj2+A647piRbSsrMtdUc1MoWZLU+53ZJ5odbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}