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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77df8d81584c8e78181021c73acca9d86bc9cdc72dffca2ea647c2433f6922de' 
  AND token = 'TCstM9PCG9jfrzUPWcoCJhA+jNi83FVAIKt7yMtbK38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}