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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0849e9e072b440c224c271ec08da044ef0a5e0025684265237ee62b4a026ae7' 
  AND token = 'Hmq2zvGR2QrvypdczQ6sr/ccLqpWKPI7muiH6xBtnSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}