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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844a39296b9a2bb875ade8df5b8d845e5b66ee13565849a47b7cad13136c2939' 
  AND token = 'izjkqpdV6A+WRwQpe7Kdq8cURUh2fm7iYiBeOZA3r+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}