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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e756dfb77192ccc3f62a541957b7f1e7f7464b736deccd5844028caa27773004' 
  AND token = '1ZMOADYMUVq0H6D7OwWWFHIPLK6YeDh8vOspkFxleSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}