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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '590387ac165453b434e39f267a0ec0346680420d745934922ef941fb427c62b7' 
  AND token = 'I0LH0+DL2LMmw4nMhVbPI5+nDD7RZj2jYsiSzNsMJzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}