SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49dd0313771d176c6a939210942c585d5c5536881a205b7cd2eeecbc95d072f6' 
  AND token = '0Y84/0ipAGC2Dj9NTDKCVCqV//Mt5mwor9Bqy3zQtGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}