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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42764c48a7179fb72d2f8cd0b6e6c56f7db89270724341612456510622cac21' 
  AND token = 'QM3tY6euepw4B+6WMPatRwu7C9kBoAJHXvCdafEqqCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}