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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cebb0480c3596637f1fff086054d9db11f6acdd9bcf380191ebd0a72d6c8cba' 
  AND token = '66f3PTWs38h/i+swhFAkx5FoSQmVmQehv8AKxlKMZ78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}