SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc455356bc1c0d283acc497efa1c55bcc7be73c57e73e523463c5d713c1f6302' 
  AND token = 'RrkGw2bIuvnbLJ6GM3xZytuMS9YEg+DRCOYrqPf6OOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}