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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e393d27f2d13b8894bae965ef8e9fc21bd8eebc233e62cf23e1fa45a8195eeb' 
  AND token = '5c1mswGF6TyJ4LAmn8m/MRWUUGFMRV59nnO++ZueOzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}