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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '216c76e7b30e13273c45e7669f4c7cfcca55cbbb9faaf6e889a06b2b9eae473c' 
  AND token = '5AGZ/MsG5iY9HdaojfiBh4nM9sMTVbb7ibFi4NQGIWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}