SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e28f990a7e58e1d392530625e99aabfbf0ef97597215a0421ad42082186dd0' 
  AND token = 'KdXstcmW8mKIF7d48Yg/pD+5lLTn3jWrPhq1I7F4pog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}