SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41451292c7d5f43ba1d6bd9620ac6db04c209c55b7902113030dc58d82f3fa7' 
  AND token = 'zY5GbS5i8oyWk0aPa+tG9c7m8ZkXdBW1/X+YuniGv8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}