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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25d94b4cc0c379799f7b4d304f6a85cb0abe9b2b52690e1d1a04681ec705337' 
  AND token = 'vIbf+nbwMGnHknqTU0q5wrS5PTxOlVLgi0K7Ai2XkkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}