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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5a94918036cb9023e3ba5994e2ceae12a90c4ef385a940091d0b39a3d24116' 
  AND token = 'M6nD8YmrGoKMEE3P3nvvuMQeCQ3J7YgpFy2NzOSDdPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}