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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49aed217bd65e5d3362e8cbf6390776e0b19a1d68ee3f64835ed66e2d8ed2147' 
  AND token = 'aG71f06IqDyfL+rQm2MfQWv2WrJ5p52Ijv+iObXprp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}