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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b25c0b1bdc85c8ae428049a2b19896b755cbff63c9ee044c0a1d249e578a04' 
  AND token = '2vQcgBA6USHEFmFAqn94A3F573eFjT/bCytaQB0jFeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}