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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa91291d842afb7c3d57b3125f97110cd7e76849d522eff8e0a88bfc4f5acfa' 
  AND token = '2PlUlIzBerNzcB+FaqZYCmIcNImT3x/CwaMLm4XQtOc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}