SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3491df7a663273bef2088e2086964696277cd57c2aa0ec6eb0ff748a9cc15477' 
  AND token = 'TF5o7Jqq7lFEEh79KFnjA/l2g7bha/im5UCg8aRM0Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}