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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22542a2d53557d5979923c8b51f323edad6ea83ba4d244a74616867b5c3f3e93' 
  AND token = 'gLFEg4mF5f/gOL/ox4bVVA8iqPvYlxc+oetEs5utp7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}