SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb7252707b4f9b94e13e396ec3dc9d12a2b277e46022b9baac333b36cfa6ddf2' 
  AND token = 'sD1PI0zGoqeb1wfHjxBRQacd9RcOG5L/jjKF+I+6y0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}