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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493620bbe0d5f5bd1e816b9dcb13135750f03d3066c41281285d85aa8d27eec9' 
  AND token = 'EodazTb23ib5lVjOo3qMLcykWv/K0EQ1OogTYZ75ZwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}