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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e759a5118a2f57c0febe87d6c271d8193845517161bc055c19fcc322bf178b' 
  AND token = 'xr5g58v8ZeAIXFcThFdgw/nvzxtnzV9Xn9fmtePfp7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}