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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7f2d8c593605731c2b544fc76ebef6373893ebe2901f24e8381d227cf426caa' 
  AND token = 'hlNtxgnz4Sv2y79clbEP2KaiQgZPVQJOabsnus8UdEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}