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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8481ccf8e8bc00a8251e46cec2581565daad3ece5cc04eda263b4af832ba80' 
  AND token = 'WczXMhWQ9QYYKz7ovgbbxrSs4UeN/Q7sVP1uPQzXh9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}