SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afbb5f1b7eb28db0b3b31de4cf9900a5256c1214c9e542838950213409a78bcf' 
  AND token = '+nmoNR+rmUc/l+Dbp0zM6HeNRY2yII40+UkkKwI1iVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}