SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fdf769edca8a9ebe4fe6a12b2c112d0346edc1f3cddb76345b7eb6da8989ba9' 
  AND token = 'vcP8ecutQVkaI5/ENsJ5VPphlYrCMhGkIfRLLHmSzwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}