SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d662c7ce091a5b2344013cb3a58caa375b08ffef0a385953ba2d445ff2abe43' 
  AND token = 'Ga0d9F0VEhZCy1lIhp09eThloQKgekC3ZXQsUJAQdAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}