SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '011e145238135dc90111f0846617e02a6488db7a0880f2401addda25c143770f' 
  AND token = '71QYHutALeFTB0h4rk4X7p4W7fs491P24w+RPWWUp2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}