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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93687f13075b0f2785f71de1a5598dedf636d90cce4407fd7349d180c62a5144' 
  AND token = 'eZ9XuTtqw7xSlCRW7dFl8xzyrq3GB+IEjHaaF+MIMQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}